Authors
Citation
Ja. Walker et P. Quirke, Viewing apoptosis through a 'TUNEL', J PATHOLOGY, 195(3), 2001, pp. 275-276
Citations number
15
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF PATHOLOGY
ISSN journal
00223417
→ ACNP
Volume
195
Issue
3
Year of publication
2001
Pages
275 - 276
Database
ISI
SICI code
0022-3417(200110)195:3<275:VATA'>2.0.ZU;2-H
Abstract
Apoptosis has an important role in carcinogenesis and cancer treatment. The
end result of this complex pathway is the formation of apoptotic bodies. T
hese can be difficult to quantify accurately, but quantitation is important
if we wish to study this process. Several techniques are available which c
an help. 'TUNEL' is discussed, with its potential drawbacks, and newer anti
body techniques, such as M30 and caspase 3, are then reviewed. Copyright (C
) 2001 John Wiley & Sons, Ltd.