This study examined the causal relationship between substance use and delin
quency. Subjects were 596 males aged 16 to 19 from Buffalo, New York. Two i
nterviews were conducted 18 months apart. Cross-lagged and synchronous stru
ctural equation panel models were fit for both early and late onset of deli
nquency groups with five types of delinquency: minor general, serious, prop
erty, and violent offenses. The results showed a significant difference bet
ween early-onset and late-onset groups concerning the relationship between
substance use and delinquency. Early-onset models showed no causal relation
ship between substance use and delinquency. The late-onset models showed th
at minor offenses have significant lagged and synchronous positive effects
on drug use, drug use exhibited significant lagged and synchronous positive
effects on general offenses, and drinking has significant lagged and synch
ronous negative effects on property offenses. The implications of these fin
dings are discussed.