T. Misawa et al., HOW TO DECREASE FALSE-POSITIVE CASES OF OVARIAN-CANCER SCREENING BY TRANSVAGINAL SONOGRAPHY, Journal of experimental & clinical cancer research, 16(2), 1997, pp. 217-220
Screening for ovarian cancer is an important step in improving ovarian
cancer mortality. This is a report of screening for ovarian cancer us
ing transvaginal sonography (TVS) on 2,095 asymptomatic women during t
he past four years. Ovarian tumors over 30mm in diameter were detected
in 87 women (4.2%). Fourteen tumors were morphologically classified a
s complex type and 73 as cystic type. Only 12 tumors were palpable on
bimanual vaginal examination. Seven women with complex type tumors und
erwent laparotomy and their pathological diagnoses revealed 3 dermoid
cysts, 3 endometrioid cysts and 1 ovarian cancer. Two women with cysti
c type tumors underwent laparotomy and their pathological diagnoses re
vealed 1 paraovarian cyst and 1 endometrioid cyst. Many ovarian tumors
were detected at prolonged cycle of menstruation and 69% of them disa
ppeared in repeated TVS. Sixty percent of ovarian cystic tumors under
50mm in diameter also disappeared in repeated TVS. Close attention to
menstrual cycle and morphologic findings is needed to decrease false-p
ositive cases in TVS screening for ovarian cancer.