Impaired auditory recognition memory in amnesic patients with medial temporal lobe lesions

Citation
Lr. Squire et al., Impaired auditory recognition memory in amnesic patients with medial temporal lobe lesions, LEARN MEM, 8(5), 2001, pp. 252-256
Citations number
33
Categorie Soggetti
Neurosciences & Behavoir
Journal title
LEARNING & MEMORY
ISSN journal
10720502 → ACNP
Volume
8
Issue
5
Year of publication
2001
Pages
252 - 256
Database
ISI
SICI code
1072-0502(200109/10)8:5<252:IARMIA>2.0.ZU;2-D
Abstract
Two tests of auditory recognition memory were given to four patients with b ilateral hippocampal damage (H+) and three patients with large medial tempo ral lobe lesions and additional variable damage to lateral temporal cortex (MTL+). When single stimuli were presented, performance was normal across d elays as long as 30 sec, presumably because information could be maintained in working memory through rehearsal. When lists of 10 stimuli were present ed, performance was impaired after a 5-min delay. Patients with MTL+ lesion s performed marginally worse than patients with H+ lesions, consistent with findings for recognition memory in other modalities. The findings show tha t auditory recognition, like recognition memory in other sensory modalities , is dependent on the medial temporal lobe.