Liver transplantation, a resource-intensive medical procedure, is under par
ticular scrutiny in the current era of cost containment. There have been si
gnificant changes in treatment protocols over the past decade; however, inf
ormation is limited on how these changes have affected the economics of liv
er transplantation. This study examines a time series from 1993 to 1999 in
Medicare expenditures for liver transplantation. We estimated total first-
and second-year expenditures, as well as expenditures 90 days pretransplant
ation. These expenditures included inpatient, outpatient, physician, home h
ealth, and hospice care; immunosuppression expenditures were not estimated.
Average first-year expenditures (in year 2000 dollars) for liver transplan
tation, excluding immunosuppressives, decreased from $201,677 in 1993 to $1
43,363 in 1998. Inpatient costs accounted for the majority of total expendi
tures, decreasing from $179,306 in 1993 to $120,445 in 1998. Total days of
hospitalization decreased from 56.7 days in 1993 to 42.2 days in 1998. The
majority of hospitalization occurred during the first 90 days posttransplan
tation, but decreased from 44.4 days in 1993 to 29.4 days in 1999. Substant
ial cost reductions over this period were a result of reduced hospitalizati
on and occurred while survival rates gradually improved.