We investigated the interleukin (IL-4) levels in BALB/c mice immunized with
Anisakis extract in single or multiple doses and in mice orally infected w
ith a larva. From animals immunized maximum responses were obtained with th
e multiple doses with an only IL-4 peak. Conversely, in the mice inoculated
with a larva per os, the IL-4 levels showed two peaks of different rates.