IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms

Authors
Macpherson, AJ Hunziker, L McCoy, K Lamarre, A
Citation
Aj. Macpherson et al., IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms, MICROBES IN, 3(12), 2001, pp. 1021-1035
Citations number
119
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
3
Issue
12
Year of publication
2001
Pages
1021 - 1035
Database
ISI
SICI code
1286-4579(200110)3:12<1021:IRITIM>2.0.ZU;2-T
Abstract
IgA is the most abundant immunoglobulin produced in mammals; most is secret ed as a dimer across mucous membranes. This review discusses the different mechanisms of induction of IgA, and its role in protecting mucosal surfaces against pathogenic and non-pathogenic microorganisms. (C) 2001 Editions sc ientifiques et medicales Elsevier SAS.