H. Gershon et al., Preparation and fungitoxicity of some trichloro-, tribromo-, tetrachloro-,and tetrabromo-8-quinolinols, MONATS CHEM, 132(9), 2001, pp. 1075-1080
3,5,6-, 3,5,7-, 4,5,7-, and 5,6,7-trichloro- and -tribromo-8-quinolinols as
well as 3,5,6,7-tetrachloro- and -tetrabromo-8-quinolinols were prepared a
nd tested against six fungi (Aspergillus niger, Aspergillus oryzae, Myrothe
cium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton
mentagrophytes) in Sabouraud dextrose broth. The compounds strongly inhibit
five fungi but not M. cirinelloides. They are less active than the related
dichloro-8-quinolinols which is attributed to steric hindrance.