Mi. Oshtrakh et al., MOSSBAUER AND POSITRON-ANNIHILATION STUDIES OF STRUCTURAL MODIFICATIONS OF HEMOGLOBIN IN SOLUTION, Journal of radioanalytical and nuclear chemistry, 190(2), 1995, pp. 243-249
Structural modifications of human adult oxyhemoglobin in concentrated
solution were studied by Mossbauer and positron life-time spectroscopi
es. The effects of non-sterile degradation and irradiation by gamma-ra
ys were compared by both techniques. It was found that positron annihi
lation parameters were sensitive to the structural modifications of he
moglobin molecules in solution and could be related with the conformat
ional states of hemoglobin.