We describe orientifold operation defining O3 plane in the conifold backgro
und by deriving it from that of O4 plane in the Type IIA brane construction
by T-duality. We find that both O3(+) and O3(-) are at the tip of the cone
so that there is no net untwisted RR charge. RG analysis shows that we nee
d two 'fractional' branes for the conformal invariance in orientifolded con
ifold. We argue that the gravity solution is the same as Klebanov and Tseyt
lin since SUGRA cannot distinguish the orientifolds and D branes in this ca
se. We describe the duality cascade as well as the quantum deformation of t
he moduli space of the field theory in the presence of the orientifold. The
finitely resolved conifold does not allow the orientifold, while deformed
conifold leaves us an unresolved issue on supersymmetry. (C) 2001 Elsevier
Science B.V. All rights reserved.