Radio-frequency thermal ablation is one of the most promising minimally inv
asive techniques for the treatment of nonresectable hepatic tumors. Essenti
al technical tips to successful radio-frequency ablation therapy were colle
cted from five international experts. They were organized into five categor
ies: understanding the mechanisms and principles of radio-frequency ablatio
n, modulation of tissue physiologic characteristics to increase tumor destr
uction, strategies of overlapping ablations, strategies to improve ablation
according to tumor location, and imaging strategies after ablation to ensu
re adequate therapy. Established factors for optimal ablation, as well as e
merging technical tips, are addressed with illustrations in each section. T
hese essential tips will be very helpful for physicians performing radio-fr
equency ablation of hepatic tumors.