Ultrasonography (US) is of value in the evaluation and characterization of
breast masses in children. Most masses represent either normal breast tissu
e, cysts, or fibroadenomas. Premature thelarche may be unilateral, and norm
al breast tissue is found at US. Cysts are commonly retroareolar; when they
become infected, they appear sonographically as a complex mass. Fibroadeno
ma is the most frequent breast tumor in adolescent girls, and it is usually
solitary, homogeneous, and hypoechoic. Malignant breast lesions are very r
are in children; most are due to metastatic disease secondary to rhabdomyos
arcoma, leukemia, lymphoma, and neuroblastoma, and their US appearance is n
onspecific. Gynecomastia in boys can be mimicked by general obesity and pec
toral hypertrophy; US is helpful in the diagnosis, especially when gynecoma
stia is asymmetric. Most breast lesions in children and adolescents are ben
ign, and surgery should be avoided to prevent later deformity. US is the id
eal imaging modality to evaluate breast lesions and may be used to guide a
fine-needle aspiration biopsy. Color Doppler US evaluation is helpful; cyst
s are avascular, fibroadenomas may be avascular or hypovascular, and absces
ses show peripheral increased flow. Bloody nipple discharge is more common
in prepubertal patients, may occur in infants, and may be secondary to mamm
ary ductal ectasia. Discharge commonly resolves spontaneously, and findings
at US are frequently normal.