Benign primary cardiac neoplasms are rare but may cause significant morbidi
ty and mortality. However, they are usually treatable and can often be diag
nosed with echocardiography, computed tomography (CT), or magnetic resonanc
e (MR) imaging. Myxomas typically arise from the interatrial septum from a
narrow base of attachment. Fibroelastomas are easily detected at echocardio
graphy as small, mobile masses attached to valves by a short pedicle. Cardi
ac fibromas manifest as a large, noncontractile, solid mass in a ventricula
r wall at echocardiography and as a homogeneous mass with soft-tissue atten
uation at CT. They are usually homogeneous and hypointense on T2-weighted M
R images and isointense relative to muscle on T1-weighted images. Paragangl
iomas usually appear as large, echogenic left atrial masses at echocardiogr
aphy and as circumscribed, heterogeneous masses with low attenuation at CT.
These tumors are usually markedly hyperintense on T2-weighted MR images an
d iso- or hypointense relative to myocardium on T1-weighted images. Cardiac
lipomas manifest at CT as homogeneous, low-attenuation masses in a cardiac
chamber or in the pericardial space and demonstrate homogeneous increased
signal intensity that decreases with fat-saturated sequences at TI-weighted
MR imaging. Cardiac lymphangiomas manifest as cystic masses at echocardiog
raphy and typically demonstrate increased signal intensity at T1- and T2-we
ighted MR imaging. Familiarity with these imaging features and with the rel
ative effectiveness of these modalities is essential for prompt diagnosis a
nd effective treatment.