Laparoscopic live donor nephrectomy (LDN) was conceived as a means for decr
easing donor nephrectomy morbidity and reducing disincentives for kidney do
nation. Since LDN was first reported in 1995, explosive growth has led to i
ts performance at more than 100 centers worldwide. Despite initial skeptici
sm in some segments of the transplant community, the results of LDN have im
proved progressively so that it is emerging as a new standard of care for E
ve kidney donation. We review the development and refinement of LDN and its
current rationale and applications.