Concern over the inherent inefficiency of solute removal by conventional pe
ritoneal dialysis (PD) has led to renewed interest in continuous flow PD (C
FPD). We present clinical data from two experiences with CFPD. Ln the first
, two catheters were used to recirculate a fixed intraperitoneal volume thr
ough an external circuit comprised of a standard hemodialysis system. The s
econd patient had a dual-lumen PD catheter and was studied during two sessi
ons of flow-through PD (FTPD) using sterile PD solution. Urea clearances wi
th both techniques were around 30 ml/min, which is consistent with data rep
orted in the literature, Significant streaming of dialysate from port to po
rt within the peritoneal cavity limited clearances, CFPD offers a potential
ly safe and effective alternative to daily or nightly home hemodialysis.