Synthesis and vesicle formation of ethyl 2-[2 '-(F-alkyl)ethyl] 2-alkyl malonic acid disodium salts

A series of new di-anionic perfluoroalkylated amphiphiles with mixed F-alky l/alkyl long chains and a malonic acid disodium salt head group has been sy nthesized. Among these new F-alkyl-containing amphiphiles, some were found to self-assemble in stable vesicles by hand shaking in water at room temper ature. The vesicular aggregates were viewed by freeze-fracture electron mic roscopy and measured with photon correlation spectroscopy. Surface-activity of all amphiphiles was also investigated. Their CMCs were in particular de termined from curves giving surface tension versus concentration.