An expedient one-step preparation of (S)-2,3-O-isopropylideneglyceraldehyde

Authors
Ermolenko, L Sasaki, NA Potier, P
Citation
L. Ermolenko et al., An expedient one-step preparation of (S)-2,3-O-isopropylideneglyceraldehyde, SYNLETT, (10), 2001, pp. 1565-1566
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
10
Year of publication
2001
Pages
1565 - 1566
Database
ISI
SICI code
0936-5214(200110):10<1565:AEOPO(>2.0.ZU;2-3
Abstract
One-step PCC oxidation of (R)-2,3-O-isopropylideneglycerol in dichlorometha ne provides (S)-2,3-O-isopropylideneglyceraldehyde 2 in 30% yield after its separation from ester 3 by careful distillation. The same procedure with ( S)-2,3-O-isopropylideneglycerol affords (R)-2,3-O-isopropylideneglyceraldeh yde.