Pd-catalyzed asymmetric allylation with a novel C-2-symmetric bisphosphinite ligand: 3R,3 ' R-bis(diphenylphosphinoxy)-6,6,6 ',6 '-tetramethyl-2S,2 'S-di-4H-pyran

Authors
Zhang, RZ Yu, LB Xu, L Wang, ZQ Ding, KL
Citation
Rz. Zhang et al., Pd-catalyzed asymmetric allylation with a novel C-2-symmetric bisphosphinite ligand: 3R,3 ' R-bis(diphenylphosphinoxy)-6,6,6 ',6 '-tetramethyl-2S,2 'S-di-4H-pyran, TETRAHEDR L, 42(43), 2001, pp. 7659-7662
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
43
Year of publication
2001
Pages
7659 - 7662
Database
ISI
SICI code
0040-4039(20011022)42:43<7659:PAAWAN>2.0.ZU;2-U
Abstract
A novel C-2-symmetric chiral bisphosphinite ligand, 3R,3'R-bis(diphenylphos phinoxy)-6,6,6',6'-tetramethyl-2S,2'S-di-4H-pyran, was synthesized from D-m annitol and examined for palladium-catalyzed asymmetric allylic substitutio n. Under the optimized conditions, the allylation product can be obtained i n up to 91.2% ee. (C) 2001 Elsevier Science Ltd. All rights reserved.