Citation
G. Aranda et al., Microbiologically-assisted hemisynthesis of 1 alpha-hydroxydrimenol, TETRAHEDR-A, 12(14), 2001, pp. 2013-2018
Citations number
55
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166
→ ACNP
Volume
12
Issue
14
Year of publication
2001
Pages
2013 - 2018
Database
ISI
SICI code
0957-4166(20010814)12:14<2013:MHO1A>2.0.ZU;2-Q
Abstract
The hemisynthesis of 1 alpha -hydroxydrimenol has been selected to illustra
te a synthetic route involving an initial microbial 3 beta -hydroxylation o
f a drimenol derivative followed by a functionalization transfer to positio
n 1 alpha, thus generating a new potentially bioactive hydroxylated terpeni
c compound, Several methods have been investigated for the protection and t
he regeneration of the 7,8-double bond of drimenyl derivatives. (C) 2001 El
sevier Science Ltd. All rights reserved.