Camphor-derived amber/woody odorants: 1,7,7-trimethyl-2 '-iso-propylspiro[bicyclo[2.2.1]heptane-2,4 '(1,3-dioxanes)]

Authors
Bajgrowicz, JA Frank, I
Citation
Ja. Bajgrowicz et I. Frank, Camphor-derived amber/woody odorants: 1,7,7-trimethyl-2 '-iso-propylspiro[bicyclo[2.2.1]heptane-2,4 '(1,3-dioxanes)], TETRAHEDR-A, 12(14), 2001, pp. 2049-2057
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
14
Year of publication
2001
Pages
2049 - 2057
Database
ISI
SICI code
0957-4166(20010814)12:14<2049:CAO1'>2.0.ZU;2-Z
Abstract
Six stereoisomers of a new camphor-derived 1,7,7-trimethyl-2'-iso-propylspi ro[bicyclo[2.2.1]heptane-2,4'-(1,3-dioxane)] odorant were prepared. Their d esign with the help of an amber olfactophore model and structure-odour rela tionship are reported. The (IR,2S,4R,2'S) isomer has by far the strongest a nd the most characteristic amber-like odour. (C) 2001 Elsevier Science Ltd. All rights reserved.