During observation of 100 patients with consequences of different types of
drug-addictions (heroin, opium, poly-drug, pervitine-ephedrine) a complex o
f social and biological factors was analyzed: heredity, premorbid personali
ty, somatic diseases, nurture, age of the onset of drug-addiction, duration
of drug abuse, asocial behavior. influence of these factors was studied ac
cording to the following parameters: alterations of personality; degree of
the moral-ethic decline and of the intellectual-mnestic disorders; somatic
complications; the presence of the suicidal trends; frequency of self-damag
es; a professional level; family interrelations; frequency of the delinquen
cies (including conviction). On the basis of the correlation analysis it wa
s established that the most significant unfavorable prognostic factors, whi
ch had determined a rate of the formation of the addictive personality were
the following (in order of the decrease of significance): perinatal pathol
ogy; family history of alcoholism, drug-addiction and other mental diseases
; personality deviations in premorbid period; an early age of the onset of
drug addiction; a type of the drug; education; alcoholic abuse before the a
ddiction; duration of the addiction.