Anemia in children

Citation
Jj. Irwin et Kt. Kirchner, Anemia in children, AM FAM PHYS, 64(8), 2001, pp. 1379-1386
Citations number
24
Categorie Soggetti
General & Internal Medicine
Journal title
AMERICAN FAMILY PHYSICIAN
ISSN journal
0002838X → ACNP
Volume
64
Issue
8
Year of publication
2001
Pages
1379 - 1386
Database
ISI
SICI code
0002-838X(20011015)64:8<1379:AIC>2.0.ZU;2-F
Abstract
Anemia in children is commonly encountered by the family physician. Multipl e causes exist, but with a thorough history, a physical examination and lim ited laboratory evaluation a specific diagnosis can usually be established. The use of the mean corpuscular volume to classify the anemia as microcyti c, normocytic or macrocytic is a standard diagnostic approach. The most com mon form of microcytic anemia is iron deficiency caused by reduced dietary intake. It is easily treatable with supplemental iron and early interventio n may prevent later loss of cognitive function. Less common causes of micro cytosis are thalassemia and lead poisoning. Normocytic anemia has many caus es, making the diagnosis more difficult. The reticulocyte count will help n arrow the differential diagnosis; however, additional testing may be necess ary to rule out hemolysis, hemoglobinopathies, membrane defects and enzymop athies. Macrocytic anemia may be caused by a deficiency of folic acid and/o r vitamin B-12, hypothyroiclism and liver disease. This form of anemia is u ncommon in children.