G. Voggenreiter et al., ESTIMATION OF CONDENSED PULMONARY PARENCHYMA FROM GAS-EXCHANGE PARAMETERS IN PATIENTS WITH MULTIPLE TRAUMA AND BLUNT CHEST TRAUMA, The journal of trauma, injury, infection, and critical care, 43(1), 1997, pp. 8-12
Pulmonary gas exchange in correlation with condensed lung volume was p
rospectively studied in 10 patients with multiple injuries and blunt c
hest trauma, The purpose was to find nomograms that allow the estimati
on of the extent of pulmonary density from gas exchange parameters, Th
e condensed lung volume was determined planimetrically from serial tra
nsverse sections of chest computed tomographic scans, There was no cor
relation between condensed lung volume and mean pulmonary artery press
ure, pulmonary vascular resistance, systemic vascular resistance, or c
ardiac index and a week negative correlation to the oxygenation index
(Pao(2)/Fio(2)) (r(2) = 0.46) and to the total static lung compliance
(r(2) = 0.29), A strong correlation between pulmonary density and intr
apulmonary shunt fraction (Qs/Qt) (r(2) = 0.95) as well as alveoloarte
rial Po-2 difference (P(A-a)o(2)) (r(2) = 0.86) was evident, By using
linear regression equations (linear regression line with 95% confidenc
e interval), nomograms were calculated, The extent of pulmonary densit
y can easily be obtained from these nomograms by measuring Qs/Qt or P(
A-a)o(2). The presented nomograms may be helpful in monitoring the eff
ect of treatment in patients with blunt chest trauma.