The risk of adenoid hypertrophy in children with allergic rhinitis

Background: Adenoid hypertrophy (AH) may cause significant morbidity in chi ldren but its relationship to allergic rhinitis (AR) has not been studied. Objective: To determine the risk factor of AH in patients with AR. Methods: We studied 315 children (ages 1 to 18 years) who had AE and AR. We compared them with 315 age-matched controls who had AR alone. To identify risk factors, they were. divided into four groups according to age and clin ical parameters, including the prevalence of otitis media, sinusitis, lower respiratory infection, exposure to smoking, sleep disorders, use of antihi stamine/decongestants, and results of allergy skin testing. Results: The prevalence of upper or lower respiratory infections was higher in the group with AR and AH, but not in all age groups. A high prevalence of exposure to smoking and skin test reactivity against house dust mites we re found in both groups. However, the prevalence of positive reactivity to molds was significantly higher in the group with AH and AR (P ranged from 0 .013 to <0.0001 and the relative risk ranged from 1.609 to 2.375). Further, the risk of AH was positively correlated with number of skin test reactivi ty to mold spores (P ranged from 0.0035 to 0.0001). Positive skin test reac tivity to animal danders or seasonal allergens failed to predict the risk o f AH. Conclusions: Sensitivity to mold allergens is an important risk factor for AH in children with AR; therefore, early prevention of exposure to molds ma y help reduce occurrence of AH.