Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens

Authors
Melville, CM Scott, KP Mercer, DK Flint, HJ
Citation
Cm. Melville et al., Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens, ANTIM AG CH, 45(11), 2001, pp. 3246-3249
Citations number
19
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
11
Year of publication
2001
Pages
3246 - 3249
Database
ISI
SICI code
0066-4804(200111)45:11<3246:NTRGTI>2.0.ZU;2-L
Abstract
A novel tetracycline resistance gene, designated tet(32), which confers a h igh level of tetracycline resistance, was identified in the Clostridium-rel ated human colonic anaerobe K10, which also carries tet(W). tet(32) was tra nsmissible in vitro to the rumen anaerobe Butyrivibrio fibrisolvens 2221(R) . The predicted gene product of tet(32) has 76% amino acid identity with Te t(O). PCR amplification indicated that tet(32) is widely distributed in the ovine rumen and in porcine feces.