In vivo efficacy of telithromycin (HMR3647) against Streptococcus pneumoniae and Haemophilus influenzae

Authors
Okamoto, H Miyazaki, S Tateda, K Ishii, Y Yamaguchi, K
Citation
H. Okamoto et al., In vivo efficacy of telithromycin (HMR3647) against Streptococcus pneumoniae and Haemophilus influenzae, ANTIM AG CH, 45(11), 2001, pp. 3250-3252
Citations number
13
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
11
Year of publication
2001
Pages
3250 - 3252
Database
ISI
SICI code
0066-4804(200111)45:11<3250:IVEOT(>2.0.ZU;2-W
Abstract
The in vivo activity of telithromycin against erythromycin A- and penicilli n G-resistant Streptococcus pneumoniae was superior to that of azithromycin , clarithromycin, cefdinir, and levofloxacin. In respiratory tract infectio ns caused by erythromycin A-susceptible S. pneumoniae or Haemophilus influe nzae in mice, telithromycin was more effective than clarithromycin and comp arable to azithromycin.