Treatment of vancomycin-resistant enterococcal infections in the immunocompromised host: Quinupristin-dalfopristin in combination with minocycline

Authors
Raad, I Hachem, R Hanna, H Girgawy, E Rolston, K Whimbey, E Husni, R Bodey, G
Citation
I. Raad et al., Treatment of vancomycin-resistant enterococcal infections in the immunocompromised host: Quinupristin-dalfopristin in combination with minocycline, ANTIM AG CH, 45(11), 2001, pp. 3202-3204
Citations number
15
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
11
Year of publication
2001
Pages
3202 - 3204
Database
ISI
SICI code
0066-4804(200111)45:11<3202:TOVEII>2.0.ZU;2-M
Abstract
Between February 1994 and November 1998, 56 oncology patients infected with vancomycin-resistant enterococci (VRE) were treated with quinopristin-dalf opristin (Q-D) plus minocycline (MIN). Infections included bacteremia, urin ary tract infection, pneumonia, and wound infection. The response rate was 68%, and the most frequent adverse event was arthralgia or myalgia (36%). Q -D-MIN is effective for VRE infection in cancer patients but is associated with a substantial frequency of arthralgia or myalgia.