Seminal toxicity of nickel sulfate in mice

Citation
R. Pandey et Sp. Singh, Seminal toxicity of nickel sulfate in mice, BIOL TR EL, 82(1-3), 2001, pp. 211-215
Citations number
18
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
BIOLOGICAL TRACE ELEMENT RESEARCH
ISSN journal
01634984 → ACNP
Volume
82
Issue
1-3
Year of publication
2001
Pages
211 - 215
Database
ISI
SICI code
0163-4984(200122)82:1-3<211:STONSI>2.0.ZU;2-W
Abstract
Young male albino mice of Swiss strain were exposed to nickel by oral route of 20 mg nickel sulfate/kg body weight for 5 d/wk for 6 mo. A decrease in normal (testosterone-dependent) proteinuria was shown, and morphological ex amination of the seminal vesicles revealed a lower weight and smaller size as well as a histological indication of lower secretory activity of the epi thelium compared to controls. The findings are consistent with a theory imp lying a decreased testosterone activity in nickel-treated animals.