Cryptoregiochemical analysis of an unusual bacterial desaturation

Authors
Fauconnot, L Buist, PH
Citation
L. Fauconnot et Ph. Buist, Cryptoregiochemical analysis of an unusual bacterial desaturation, BIOORG MED, 11(21), 2001, pp. 2879-2881
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
21
Year of publication
2001
Pages
2879 - 2881
Database
ISI
SICI code
0960-894X(20011105)11:21<2879:CAOAUB>2.0.ZU;2-C
Abstract
The cryptoregiochemistry of the cold-induced Delta (5) desaturation of long chain fatty acids, as it occurs in Bacillus subtilis ATCC 23857, has been examined by measuring the individual primary deuterium kinetic isotope effe cts associated with the C-H bond cleavage at C-5 and C-6. The results point to C-5 as the site of initial oxidation in Delta (5) desaturation. (C) 200 1 Elsevier Science Ltd. All rights reserved.