Prophylaxis failure is associated with a specific Pneumocystis carinii genotype

Authors
Hauser, PM Sudre, P Nahimana, A Francioli, P
Citation
Pm. Hauser et al., Prophylaxis failure is associated with a specific Pneumocystis carinii genotype, CLIN INF D, 33(7), 2001, pp. 1080-1082
Citations number
10
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
33
Issue
7
Year of publication
2001
Pages
1080 - 1082
Database
ISI
SICI code
1058-4838(20011001)33:7<1080:PFIAWA>2.0.ZU;2-R
Abstract
To investigate the possible association between Pneumocystis carinii types and various clinical and demographic parameters, we used molecular typing t o analyze 93 bronchoalveolar lavage specimens from patients with P. carinii pneumonia (PCP). Multivariate regression analysis revealed an association between being infected with a specific P. carinii genotype and receiving an ti-PCP prophylaxis (odds ratio, 4.4; 95% confidence interval, 1.0-18.6; P=. 05), although no association with a specific drug was detected.