Myelitis and ascending flaccid paralysis due to congenital toxoplasmosis

Authors
Campbell, AL Sullivan, JE Marshall, GS
Citation
Al. Campbell et al., Myelitis and ascending flaccid paralysis due to congenital toxoplasmosis, CLIN INF D, 33(10), 2001, pp. 1778-1781
Citations number
22
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
33
Issue
10
Year of publication
2001
Pages
1778 - 1781
Database
ISI
SICI code
1058-4838(20011115)33:10<1778:MAAFPD>2.0.ZU;2-7
Abstract
A 4-week-old female newborn developed ascending flaccid paralysis and radio logic evidence of myelitis; the diagnosis of congenital toxoplasmosis was c onfirmed by the presence of Toxoplasma gondii-specific immunoglobulins in b oth mother and infant, and detection of Toxoplasma sequences in the infant' s cerebrospinal fluid by polymerase chain reaction analysis. Treatment with pyrimethamine, sulfadiazine, and methylprednisolone resulted in improvemen t.