The term 'Target of Opportunity' (ToO) is used in astronomy to identify unp
redictable events whose study is of the highest scientific interest. For XM
M-Newton a ToO is an astronomical event observable by its instruments, whic
h cannot be predicted and scheduled on the time scale of one year, yet is s
cientifically significant enough to justify the interruption of the ongoing
observing programme. Here we discuss the kinds of objects that are suitabl
e for observation as ToOs with XMM-Newton, their scientific interest, and h
ow they are incorporated into the overall observing schedule in terms of ta
rget selection and mission planning. What has been done so far and the prel
iminary results for a few ToO examples are then presented.