Non diethylstilbesterol induced vaginal adenosis - A case series and review of literature

Non diethylstilbestrol induced vaginal adenosis has a reported incidence of about 10% in adult women [1]. Although in some, it may be an insignificant coincidental finding, it is probably under-diagnosed even in symptomatic w omen. Little is known about the aetiology, pathogenesis, symptomatology and management of this poorly understood condition. Our experience with the fo ur cases of vaginal adenosis unrelated to diethylstilbestrol (DES) exposure and a review of the literature will probably shed some light on this, as i t still remains an enigma in gynaecological oncology.