Can intermediate-risk node-negative patients with stage I corpus cancer dowithout posthysterectomy radiotherapy? Review of a 13-year experience

A retrospective comparative study of 41 patients with stage I corpus cancer , negative surgical staging, and adverse pathological features either treat ed or untreated by posthysterectomy radiotherapy (PHR) during a 13-year per iod was undertaken. The patients were matched for age, intermediate-risk cl assification, number of sampled nodes and the presence of coexisting illnes s. After complete follow-up, there was no significant difference in outcome between the patient groups. Unless it can be shown definitely that PHR is beneficial, its use in intermediate-risk node-negative stage I corpus cance r patients must be seriously questioned.