B. Grass et al., Comparison of different conductivity detector geometries on an isotachophoresis PMMA-microchip, FRESEN J AN, 371(2), 2001, pp. 228-233
Conductivity detection is one of the most often employed means of detection
in isotachophoresis. In microanalytical devices, thin-film platinum electr
odes can be used for conductivity detection and for other electrochemical m
ethods of detection. The design and the performance of different electrode
geometries for on-column contact conductivity detection with thin-film plat
inum electrodes integrated on an isotachophoresis PMMA-microchip is describ
ed. Three different electrode geometries for direct conductivity detection
were used for the investigation of isotachophoretic separations. The influe
nce of the width of the electrodes and their positioning relative to the se
paration channel was investigated. The performance of the different detecto
rs is compared for the analysis of organic carboxylic acid anions.