High prevalence of non-virus/non-alcohol-related alanine-aminotransferase increase in blood donors

Authors
Morisco, F Di Lonardo, A Stroffolini, T Leone, D Caporaso, N
Citation
F. Morisco et al., High prevalence of non-virus/non-alcohol-related alanine-aminotransferase increase in blood donors, HAEMATOLOG, 86(10), 2001, pp. 1116-1116
Citations number
8
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
86
Issue
10
Year of publication
2001
Pages
1116 - 1116
Database
ISI
SICI code
0390-6078(200110)86:10<1116:HPONAI>2.0.ZU;2-W
Abstract
A slight increase of alanine-aminotransferase (ALT) levels is frequently ob served (23.7%) in blood donors negative for hepatitis viruses (B and C) and alcohol abuse. The highest rate of subjects with ALT abnormalities was obs erved in men 20-40 years old, with a body mass index greater than or equal to 25. Non-alcoholic fatty liver disease (NAFLD) is probably the most frequ ent cause of hypertransaminasemia in Italian blood donors.