The purpose of this paper was to examine whether quantitative bacterio
logic assessment of hone is a reliable indicator of the adequacy of de
bridement of draining wounds involving bone. This is a retrospective r
eview of 31 consecutive patients treated for draining posttraumatic/su
rgical wounds involving bone. Nineteen patients met the necessary crit
eria and were included in the study. These patients underwent radical
debridement of bone and soft tissue, intraoperative assessment of the
debrided wound by rapid slide quantitative bacteriologic assessment, a
nd closure with well-vascularized tissue. Clinical assessment of vascu
larity and rapid slide quantitative bacteriologic assessment of cancel
lous bone and soft tissue were the only prerequisites used in determin
ing the appropriateness of wound closure in this study. At the time of
most recent followup, none of the 19 patients had recurrent wound dra
inage. Two patients required a second procedure to partially elevate t
heir flaps and drain recurrent soft-tissue infections. None of the pat
ients had recurrence of bony infection. Seventeen patients who present
ed initially with fractures or osteotomies all had successful hone uni
ons. This study demonstrates that the technique of rapid slide quantit
ative bacteriologic assessment of cancellous bone is a useful adjunct
to surgical judgment and allows one to close draining wounds (frequent
ly with complex wound closure options) with a high level of confidence
.