A 4.1-kilodalton polypeptide in the cultural supernatant of Mycoplasma fermentans is one of the substances responsible for induction of interleukin-6production by human gingival fibroblasts

Authors
Hasebe, A Shibata, K Watanabe, T
Citation
A. Hasebe et al., A 4.1-kilodalton polypeptide in the cultural supernatant of Mycoplasma fermentans is one of the substances responsible for induction of interleukin-6production by human gingival fibroblasts, INFEC IMMUN, 69(11), 2001, pp. 7173-7177
Citations number
32
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
69
Issue
11
Year of publication
2001
Pages
7173 - 7177
Database
ISI
SICI code
0019-9567(200111)69:11<7173:A4PITC>2.0.ZU;2-M
Abstract
The cultural supernatant of Mycoplasma fermentans induced interleukin-6 pro duction by human gingival fibroblasts. The active entities were divided int o hydrophilic and hydrophobic substances. In this study, we purified a 4.1- kilodalton polypeptide from the hydrophilic substances. It reacted with pol yclonal antibodies to M. fermentans and activated human macrophages.