Association of Graves' disease with Evans' syndrome in a patient with IgA nephropathy

A 20-year-old woman with IgA nephropathy was admitted to Jikei University H ospital for the treatment of rapid deterioration of renal function after re ceiving I-131-therapy against hyperthyroidism on October 23,1999, and hemod ialysis was started. On admission, she was diagnosed as having Evans' syndr ome in addition to known Graves' disease. Renal biopsy revealed end-stage r enal damage, then, hemodialysis was maintained. Treatment for Evans' syndro me was also started and her general condition gradually improved. The prese nt case implied that "Graves' disease" and "Evans' syndrome" could represen t some of the manifestations of an underlying immunological disorder in the patient.