Myelodysplastic syndrome accompanied by Addison's disease and multiple autoimmune phenomena: Steroid therapy resolved cytopenias and all immune disorders

We report here a patient with myelodysplastic syndromes (MDS), which was co mplicated with several autoimmune disorders and asymptomatic immunologic ab normalities. An 82-year-old woman with refractory anemia (RA) rapidly devel oped thrombocytopenia with the appearance of symptoms such as purpura, fati gue, anorexia, and weight loss. Furthermore, clinical examinations revealed that she also had Addison's disease, rheumatoid arthritis, and autoimmune hematological diseases such as thrombocytopenia and hemolytic anemia. Howev er, the cytopenia and all autoimmune disorders were remarkably improved aft er she received steroid therapy.