Reactivity of 4-chlorobenzo[c][2,7]naphthyridines towards Pd(0) catalyzed coupling reactions and nucleophilic substitutions. Aroylation by nucleophilic substitution with analogues of acyl anions
G. Duvey et al., Reactivity of 4-chlorobenzo[c][2,7]naphthyridines towards Pd(0) catalyzed coupling reactions and nucleophilic substitutions. Aroylation by nucleophilic substitution with analogues of acyl anions, J HETERO CH, 38(5), 2001, pp. 1039-1044
Various 4-substituted benzo[c][2,7]naphthyridines were prepared from the co
rresponding 4-chloro derivative by Pd(0) coupling reaction or nucleophilic
substitution. More particularly, 4-aroyl-benzo[c][2,7]naphthyridines were s
ynthesized by aroylation with arenecarbaldehydes in the presence of 1,3-dim
ethylimidazolium iodide.