Citation
Azms. Chowdhury et al., Synthesis of new heterocondensed pteridines, J HETERO CH, 38(5), 2001, pp. 1173-1177
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X
→ ACNP
Volume
38
Issue
5
Year of publication
2001
Pages
1173 - 1177
Database
ISI
SICI code
0022-152X(200109/10)38:5<1173:SONHP>2.0.ZU;2-K
Abstract
Reaction of 2-aminopyrazine 1 with isothiocyanate. isocyanate or dithioketa
l reagent furnished pteridines 3,4 in good yield. Thioxo compound 3a was ch
lorinated, methylated and subsequently displaced by amines. A simple one-st
ep synthesis of heterocondensed pteridines 8-13 by reaction of 2-aminopyraz
ine with various imino thioacetals was described 8-13.