Synthesis and characterization of some coumarins with two hydroxy or methoxy substituents

Authors
Fall, Y Santana, L Uriarte, E
Citation
Y. Fall et al., Synthesis and characterization of some coumarins with two hydroxy or methoxy substituents, J HETERO CH, 38(5), 2001, pp. 1231-1232
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
38
Issue
5
Year of publication
2001
Pages
1231 - 1232
Database
ISI
SICI code
0022-152X(200109/10)38:5<1231:SACOSC>2.0.ZU;2-7
Abstract
The first synthesis of the 6-hydroxy-4-methoxycoumarin (5) was carried out in 25% overall yield from 6-methoxy-4-hydroxycoumarin (1) by hydrolysis of the methoxy group and subsequent selective methylation of the hydroxyl grou p at position 4. The H-1 and C-13 NMR data of compounds 1-6 are reported.