Ciprofloxacin-loaded bovine serum albumin microspheres: preparation and drug-release in vitro

Authors
Li, FQ Hu, JH Lu, B Yao, H Zhang, WG
Citation
Fq. Li et al., Ciprofloxacin-loaded bovine serum albumin microspheres: preparation and drug-release in vitro, J MICROENC, 18(6), 2001, pp. 825-829
Citations number
6
Categorie Soggetti
Pharmacology & Toxicology
Journal title
JOURNAL OF MICROENCAPSULATION
ISSN journal
02652048 → ACNP
Volume
18
Issue
6
Year of publication
2001
Pages
825 - 829
Database
ISI
SICI code
0265-2048(200111/12)18:6<825:CBSAMP>2.0.ZU;2-I
Abstract
Ciprofloxacin albumin microspheres were prepared by the spray drying techni que, with bovine serum albumin as the natural biodegradable wall material. The spherical microspheres, flowed well, were organic solvent free and in t he size range 1 similar to 5 mum. The drug release from the microspheres co uld be retarded by further thermal denaturation. The sustained-release micr ospheres were suitable for dry powder inhaled lung drug delivery systems.