Photochemically induced electron transfer (PET) catalyzed radical cyclization: A practical method for inducing structural changes in peptides by formation of cyclic amino acid derivatives

Authors
Jonas, M Blechert, S Steckhan, E
Citation
M. Jonas et al., Photochemically induced electron transfer (PET) catalyzed radical cyclization: A practical method for inducing structural changes in peptides by formation of cyclic amino acid derivatives, J ORG CHEM, 66(21), 2001, pp. 6896-6904
Citations number
53
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263 → ACNP
Volume
66
Issue
21
Year of publication
2001
Pages
6896 - 6904
Database
ISI
SICI code
0022-3263(20011019)66:21<6896:PIET(C>2.0.ZU;2-J
Abstract
A new radical cyclization reaction of unsaturated amino acid derivatives is presented. The reaction is induced by photoelectron transfer (PET) catalys is and proceeds, in comparison to commonly applied methods, under mild, non oxidizing, and nontoxic conditions in neutral medium. This type of radical cyclization reaction can be used in peptide chemistry for inducing structur al changes in peptides.