Electrolytic partial fluorination of organic compounds. 54. Anodic mono- and trifluorination of thiochroman-4-one derivatives and the factors affecting product selectivity
Km. Dawood et al., Electrolytic partial fluorination of organic compounds. 54. Anodic mono- and trifluorination of thiochroman-4-one derivatives and the factors affecting product selectivity, J ORG CHEM, 66(21), 2001, pp. 7030-7034
Anodic fluorination of (E)-3-benzylidene-2,3-dihydrothiochroman-4-one and 3
-benzyl-1-thiochromone derivatives under a variety of electrolytic conditio
ns was found to provide selectively or exclusively the same fluorinated pro
ducts: (E)-3-benzylidene-2,3-dihydro-2-fluorothiochroman-4-ones, In additio
n, di- and trifluorinated derivatives were also obtained depending on the s
tarting heterocycles and electrolytic conditions. The factors affecting the
product selectivity were also examined.