This study compared the efficacy of two approaches to treating therapy-resi
stant patellofemoral pain syndrome. In a prospective randomized study 20 pa
tients were treated for 8 weeks with 16 physiotherapeutic exercises on a ne
urophysiological basis (proprioceptive neuromuscular facilitation) while an
other 20 patients underwent a special training program using a special resi
stance-controlled knee splint for 15 min three times daily. We measured mus
cle activity on a Cybex 6000 and performed surface electromyography of the
vastus medialis and vastus lateralis muscles. Anterior knee pain was assess
ed by the Bessette and Hunter score and a visual analogue scale. An increas
e in electromyographic activity in the vastus medialis muscle and significa
nt improvement in individual comfort were observed only in those treated by
knee splint. The knee splint thus proved more effective than proprioceptiv
e neuromuscular facilitation for treating cases of patellofemoral pain synd
rome resistant to conservative therapy.