Study of the aggregation properties of a novel amphiphilic C-60 fullerene derivative

Citation
G. Angelini et al., Study of the aggregation properties of a novel amphiphilic C-60 fullerene derivative, LANGMUIR, 17(21), 2001, pp. 6404-6407
Citations number
20
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
LANGMUIR
ISSN journal
07437463 → ACNP
Volume
17
Issue
21
Year of publication
2001
Pages
6404 - 6407
Database
ISI
SICI code
0743-7463(20011016)17:21<6404:SOTAPO>2.0.ZU;2-V
Abstract
An amphiphilic C-60-derivative, AFE, characterized by the presence of the c hiral fragment Of L-acetyl carnitine in its hydrophilic appendage has been synthesized. In binary (THF/H2O) and ternary (THF/MeOH/H2O) solutions, AFE exhibits a strong tendency to self-aggregation, provided that the Hildebran d polarity index, delta, of the solvent is higher than about 15. A stable a queous solution of aggregated AFE was obtained. Partition experiments betwe en n-octanol and water show that AFE cannot be spontaneously transferred fr om water into the organic solvent (and vice versa), although it is effectiv ely "salted-out" by common electrolytes. Light scattering and reversed-phas e liquid chromatography experiments carried out on the aqueous solution of AFE suggest for the aggregates an average diameter of 120 nm.