A device for feline head positioning and stabilization during magnetic resonance imaging

Minimization of head movement and reproduction of standard head positions a re essential for reliable brain functional magnetic available currently. We describe a system that resonance imaging. Devices for stabilization and al ignment of feline preparations are not involves minimal surgery, allows for both acute and chronic atraumatic positioning, and has the potential to be used for unanesthetized animals. The device uses non-metallic materials an d stabilizes the head by means of an apparatus that fixes the head with nyl on screws and dental cement in the frontal sinuses. Application of the head -stabilizing device decreases head movements by more than a factor of ten. Anatomical images show that this device provides 3 dimensional head placeme nt at a precision comparable to that of a stereotactic frame, i.e. within 1 mm. (C) 2001 Elsevier Science Inc. All rights reserved.