The atypical pathogens in community-acquired pneumonia traditionally have i
ncluded Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella spp. Re
cent studies documenting their epidemiology and clinical characteristics ha
ve shown that these organisms are indistinguishable from the pneumococcus.
Furthermore, therapy no longer depends on the specific bacterial cause of c
ommunity-acquired pneumonia. Etiologic diagnosis is still difficult, althou
gh new methods are becoming available. This article focuses on these issues
and on why the term atypical is no longer meaningful.